Reglan (Metoclopramide) Side Effects

Recently reported side effects related to the use of Reglan (Metoclopramide) include:

 Tardive Dyskinesia (TD):

Tardive dyskinesia is a neurological syndrome that can be caused by the long-term use of neuroleptic drugs, including Reglan.  Different classes of neuroleptic drugs are prescribed for psychiatric disorders, but Reglan also has neuroleptic characteristics.
Tardive dyskinesia is most often characterized by repetitive, involuntary, purposeless movements.  Patients suffering from TD may exhibit involuntary facial gestures, such as grimacing, tongue protrusion, lip smacking, puckering and pursing, and rapid eye blinking. They may also suffer rapid and involuntary movements of the fingers, hands, arms, shoulders, legs, and trunk.   TD can even adversely affect the ability to breathe, swallow, walk, and talk.   
Tardive dyskinesia is a serious and potentially irreversible disorder.  It can be caused by Reglan and metoclopramide.

 Other Serious Side Effects:

In addition to TD, Reglan could cause the following serious side effects: 

• Mental depression
• Other types of severe movement disorders
• Unexplained abdominal pain
• Breathing problems
• Convulsions and seizures
• Cardiovascular conditions, such as elevated blood pressure or rapid pulse
• Blood problems, especially for infants
• An allergic reaction, such as swelling of the tongue, throat or hives
• Anxiety or insomnia
• Depression
• Changes in vision
• An irregular heartbeat
• Seizures or hallucinations

Other Less Serious Side Effects:

Other less serious side effects can include:

• New or increased nausea or diarrhea;
• Dizziness, drowsiness, or headache
• Confusion or disorientation
• Fluid retention such as swelling of hands or legs, bloating
• Breast tenderness or swelling
• Changes in your menstrual cycle
• Increased need to urination
• Fatigue
• Restlessness
• Irritability

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